Hyaluronic acid (Hyaluronic acid) HA, HA general merchandise its sodium salt, sodium hyaluronate. "Chinese Pharmacopoeia" and the national drug standards, called hyaluronic acid. Hyaluronic acid is by a glycoside bond to the 1:1 (molar ratio) by glucuronic acid and N-acetyl-amino-glucose disaccharide composed Sodium gluconate of a straight chain macromolecular polysaccharide. The average molecular weight of from 105 to 107.
Hyaluronic acid can improve skin physiological conditions, provide a favorable external environment for the synthesis of dermal collagen and elastic fibers, and to strengthen the supply of nutrients, play the effect of skin care beauty. The study showed that hyaluronic acid can prevent the generation of some enzymes in the cell, reducing the formation of free radicals, prevent free radical damage to cell structure, resulting in lipid peroxidation and cause aging body plays an important role: low molecular weight hyaluronic acid has anti-inflammatory, to inhibit bacteria produce, keep skin smooth; provide a suitable place for cell proliferation and differentiation, and directly promote cell growth, differentiation, reconstruction and repair. Therefore, it is as a high-end creams, lotions, lotion, beauty lotion, lipstick, foundation and other cosmetics and toiletries essential additive to humidifier moisturizing, skin rejuvenation anti-aging and anti-wrinkle anti-inflammatory effect. Cosmetic products containing this ingredient to be recognized as the the "bionic chemicals respected. Add hyaluronic acid in cosmetics have become a mainstream product of the International Day for the community.
Its role in cosmetics as: Water HA retains water in the Isomaltulose skin tissue is one of its most important physiological functions. Its theoretical water retention values of up to 500 ml / g or more, in the connective tissue of the actual water retention value of about 80ml / g. Therefore, its unique role of water to make the skin flexible, elastic; plenty of moisture to make the skin smooth and delicate. But with the growth of skin in the Age of HA decreased, resulting in tightly packed cells, collagen loca sclerosis, rough skin moist disappeared, wrinkles, loss of elasticity.
The use of cosmetics containing hyaluronic acid may play a complementary role in the storage of skin moisture, restore and keep the skin youthful luster. 2. Eliminate free radicals HA in the epidermis can clear the active oxygen radicals produced by the sun's ultraviolet radiation, to keep the skin from harm, to be known as an efficient free radical "scavenger". Skin to regeneration and repair. Pre-use can also play a preventive role. 3 lubrication and film HA is a high molecular polymer, has a sense of strong lubrication and film-forming sense. Skin care products containing HA coated lubrication obvious sense, feel good. Applied to the skin, the hydration layer of breathable film is formed on the skin surface, so that the skin to produce a good smooth feel and moist feel to play a protective effect on the skin. Containing HA and hair care products, can form a thin film on the hair surface, play a moisturizing, lubricating, hair care, eliminate static electricity and the role of the hair easy to comb, elegant and natural. Repair damage skin. Skin after prolonged sun exposure by the sun, the sun's ultraviolet rays on the skin burns caused by phenomena such as erythema, dermatitis, peeling, HA can promote the regeneration of injured parts of the skin by promoting epidermal cell proliferation and division, as well as clear the role of oxygen free radicals, sunscreen or after-sun skin care products the HA with UV absorbers mixed use, have a synergistic effect, which can reduce the ultraviolet through to repair skin damage caused by and through the small amount of ultraviolet, play the role of dual protection. Infringement of skin trauma such as burns, frozen record, HA can protect the wound site, the cells from pathogenic bacteria to speed up the recovery organization, increase immunity, improve wound healing and regeneration ability, and 5 thickening effect.
HA in an aqueous solution having a high viscosity, and its 1% aqueous solution was gelled, and can play the role of thickening and stabilizing Add in cosmetics. Hyaluronic acid in cosmetics application Gluconic acid methods and precautions Hyaluronic acid its unique physical properties has become internationally recognized as the best natural moisturizing factor, but also as penetrant effective cosmetics nutrients, to be widely used, such as creams, lotions, condensation, lotion, eye care, eliminating wrinkles, skin lightening products, sunscreen, after-sun repair products, scar repair products, anti-acne products, face cream, shampoo, hair care products in recent years. Adding different amount can be used in an amount according to need, different products, a range of 0.05 to 2.0%. Molecular weight chosen based on the performance of the product, such as a moisturizer with the choice of Mr's; as nutritional penetration, the selection of Mr smaller repair care products.
HA and compatibility properties of the other components is preferred, compatibility is also very good, and can be added to almost any aqueous cosmetic. During use should pay attention to the following: 1.HA polysaccharide is a highly nutritious, easily Ranjun must pay attention to the health and environmental health of the container with. HA dissolved into liquid try to run out of time, if there are remaining must add preservatives in the cosmetic and frozen seal the deal, save time not too long. 2.HA susceptible to UV damage easily decomposed at high temperatures, easy to absorb moisture, so the product should be dark, cold storage, dry place. HA added to the product, should be carried out later in the processing, the temperature does not exceed 60 ° C. 3.HA dissolved in water as much as Sodium gluconate possible to use soft water or deionized water, the water quality is good or bad, a direct impact on the transparency of the aqueous solution.
To accelerate the dissolution rate in water, can be dispersed in the propylene glycol or glycerol, and then add water to dissolve. 4.HA used in emulsion products, should be used in a non-ionic or anionic emulsifiers, avoid selection cationic emulsifiers, otherwise it will destroy the structure of HA, to produce turbidity precipitate. All in all, hyaluronic acid as an excellent cosmetic additives increasingly domestic cosmetics industry attention. Practice has proved that the application of hyaluronic acid in cosmetics, will be more and more widely, the prospects are veryitaconic acid impressive.
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